Immunoway/AEBSF-hydrochloride/100mg/MC0620
市场价：
¥2200.00
美元价：
1100.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
AEBSF-hydrochloride
- Catalog No.：MC0620
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- CasNo：
- 30827-99-7
- MolecularFormula：
- C8H11ClFNO2S
- Purity：
- >98%
- Target：
- Thrombin
- IC50：
- No data
- In Vitro：
- AEBSF inhibits the constitutive production of Aβ by directly inhibiting β-secretase in five different human cell lines, both neural and nonneural[1]. AEBSF, as a serine protease inhibitor, inhibits the lysis of leukemic cells by human macrophages without inhibiting macrophage secretion of TNF-α and IL-1β[2]. AEBSF also disturbs the growth of blastocysts on endometrial cells and inhibit the adhesion of HeLa cells on HUVECs by altering the protein secretion pattern[4].
- In Vivo：
- AEBSF (76.8 mg/kg daily, i.p.) results in prolongation of the survival of mice that have been given a lethal T. gondii infection[3]. AEBSF also reduces airway response and underlying inflammation in cockroach allergen-induced murine model[4].
- Fields：
- AEBSF HCl is a broad spectrum, irreversible serine protease inhibitor.
- Specificity：
- Target: Thrombin. Fields: AEBSF HCl is a broad spectrum, irreversible serine protease inhibitor.
- Source：
- Rabbit
- Dilution：
- WB 1:500-2000
- Concentration：
- >98%
- Storage Stability：
- 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
- MolecularWeight(Da)：
- 239.69
- References：
- [1]. Citron M, et al. Inhibition of amyloid beta-protein production in neural cells by the serine protease inhibitor AEBSF. Neuron. 1996 Jul;17(1):171-9. [2]. Nakabo Y, et al. Lysis of leukemic cell
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- Antibody-FAQs
- Products Images
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品牌分类
\Elisa试剂盒\
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