Immunoway/BIX01294/10mg 50mg 100mg/MC0469
市场价：
¥4960.00
美元价：
2480.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
BIX01294
- Catalog No.：MC0469
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- CasNo：
- 935693-62-2
- MolecularFormula：
- C28H38N6O2
- Purity：
- >98%
- Target：
- Histone Methyltransferase
- IC50：
- IC50: 1.9 μM (G9a Histone Methyltransferase)
- In Vitro：
- BIX-01294 (4.1 μM) treatment of G9anull ES cells results in a further reduction in H3K9me2 levels. BIX-01294 reduces H3K9me2 at several G9a target genes[1]. BIX-01294 (5 µM) reduces levels of global H3K9 methylation in pronuclear- and 2-cell-stage embryos. Embryos transiently exposed to BIX-01294 have a reduced ability to establish pregnancy[2]. BIX-01294 (1 µg/mL) causes reduction in the BrdU incorporation of fetal PASMCs. BIX-01294 treatment decreases the PASMCs migration induced by PDGF[3].
- In Vivo：
- Fields：
- BIX01294 is an inhibitor of G9a histone methyltransferase with IC50 of 2.7 μM.
- Specificity：
- Target:Histone Methyltransferase. Fields: BIX01294 is an inhibitor of G9a histone methyltransferase with IC50 of 2.7 μM.
- Source：
- Rabbit
- Dilution：
- IC50: 1.9 μM (G9a Histone Methyltransferase)
- Concentration：
- >98%
- Storage Stability：
- 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
- Other Name：
- BIX 01294; BIX01294,BIX-01294
- MolecularWeight(Da)：
- 490.64
- References：
- [1]. Kubicek S, et al. Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase. Mol Cell. 2007 Feb 9;25(3):473-81.[2]. Park KE, et al. IVMBIX-01294, an inhibitor of th
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品牌分类
\Elisa试剂盒\
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