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商品详细Immunoway/PLX5622/200mg 500mg/MC1387
Immunoway/PLX5622/200mg 500mg/MC1387
Immunoway/PLX5622/200mg 500mg/MC1387
商品编号: MC1387
品牌: Immunoway
市场价: ¥80000.00
美元价: 40000.00
产地: 美国(厂家直采)
公司:
产品分类: 多肽合成
公司分类: peptide
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

PLX5622

  • Catalog No.:MC1387
  • Data Sheet
  • MSDS
  • Support
  • Description
  • References ( 0 )
  • Protocol
    • CasNo:
    • 1303420-67-8
    • MolecularFormula:
    • C₂₁H₁₉F₂N₅O
    • Purity:
    • >98%
    • Target:
    • CSF1R
    • IC50:
    • Animal Model: C57BL/6 mice (males, 10-12 weeks old, 20-25 g)Dosage: 65 mg/kgAdministration: Oral gavage; daily; for 14 daysResult: Caused paw withdrawal threshold high in mice, and prevented the development of injury-associated mechanical allodynia.
    • In Vitro:
    • DMSO : 41.67 mg/mL (105.38 mM; Need ultrasonic) H2O : < 0.1="" mg/ml="">
    • In Vivo:
    • PLX5622 (oral gavage; 65 mg/kg/day; for 14 days) causes paw withdrawal threshold high in mice, indicating that PLX5622 prevents the development of injury-associated mechanical allodynia
    • Fields:
    • PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor with an Ki of 5.9 nM, for extended and specific microglial elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals
    • Source:
    • Rabbit
    • Dilution:
    • WB 1:500-2000
    • Concentration:
    • >98%
    • Storage Stability:
    • Powder -20°C 3 years4°C 2 yearsIn solvent -80°C 6 months-20°C 1 month
    • MolecularWeight(Da):
    • 395.41
    • June 19-2018
    • WESTERN IMMUNOBLOTTING PROTOCOL
    • June 19-2018
    • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
    • June 19-2018
    • IMMUNOFLUORESCENCE PROTOCOL
    • September 08-2020
    • FLOW-CYTOMEYRT-PROTOCOL
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
    • July 13-2018
    • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
    • July 13-2018
    • Antibody-FAQs
    品牌介绍
    ImmunowayImmunoWay Biotechnology,我们的使命是帮助世界各地的生命科学研究人员通过更好的产品和服务简化和加速他们的研究。我们专注于开发用于免疫学和细胞学检测的创新和可靠的产品。我们一直是开发高质量ELISA试剂盒,代谢检测试剂盒,抗体和抗体/蛋白质微阵列的先驱,参与癌症,细胞凋亡,细胞生长和信号转导。ImmunoWay Biotechnology,我们的使命是通过更好的产品和服务帮助世界各地的生命科学研究者简化和加速他们的研究。我们专注于开发创新和可靠的产品,用于免疫学和细胞学检测。我们一直是开发涉及癌症,细胞凋亡,细胞生长和信号转导的高质量ELISA试剂盒,代谢测定试剂盒,抗体和抗体/蛋白质微阵列的先驱。