Immunoway/14-3-3 ε Polyclonal Antibody/50ug 100ug/YM3355
市场价：
¥3200.00
美元价：
1600.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
14-3-3 ε Polyclonal Antibody
- Catalog No.：YM3355
- Applications：WB,IHC-p,IF(paraffin section)
- Reactivity：Mouse,Rat
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name：
- YWHAE
- Protein Name：
- 14-3-3 protein epsilon
- Human Gene Id：
- 7531
- Human Swiss Prot No：
- P62258
- Mouse Swiss Prot No：
- P62259
- Rat Swiss Prot No：
- P62260
- Immunogen：
- Recombinant Protein of 14-3-3 ε
- Specificity：
- The antibody detects endogenous 14-3-3 ε protein.
- Formulation：
- PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
- Source：
- Rabbit
- Dilution：
- WB: 1:1000 IHC:1:200-500
- Purification：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability：
- -20°C/1 year
- Other Name：
- YWHAE; 14-3-3 protein epsilon; 14-3-3E
- Observed Band(KD)：
- 28
- Background：
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon(YWHAE) Homo sapiensThis gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008],
- Function：
- function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.,similarity:Belongs to the 14-3-3 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer. Heterodimerizes with YWHAZ. Interacts with NDEL1, RGNEF and TIAM2 (By similarity). Interacts with HCV core protein. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Weakly interacts with CDKN1B.,
- Subcellular Location：
- mitochondrion,cytosol,kinesin complex,cell-cell adherens junction,focal adhesion,membrane,axon,cytoplasmic vesicle membrane,melanosome,extracellular exosome,
- Expression：
- B-cell lymphoma,Brain,Cajal
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- September 08-2020
- FLOW-CYTOMEYRT-PROTOCOL
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
- July 13-2018
- Antibody-FAQs
- Products Images
- Western blot analysis of 1) Mouse Brain, 2) Rat Brain using 14-3-3 ε Polyclonal Antibody.. Secondary antibody(catalog#：RS0002) was diluted at 1:20000
- Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using 14-3-3 ε Polyclonal Antibody.
品牌介绍
ImmunowayImmunoWay Biotechnology，我们的使命是帮助世界各地的生命科学研究人员通过更好的产品和服务简化和加速他们的研究。我们专注于开发用于免疫学和细胞学检测的创新和可靠的产品。我们一直是开发高质量ELISA试剂盒，代谢检测试剂盒，抗体和抗体/蛋白质微阵列的先驱，参与癌症，细胞凋亡，细胞生长和信号转导。ImmunoWay Biotechnology，我们的使命是通过更好的产品和服务帮助世界各地的生命科学研究者简化和加速他们的研究。我们专注于开发创新和可靠的产品，用于免疫学和细胞学检测。我们一直是开发涉及癌症，细胞凋亡，细胞生长和信号转导的高质量ELISA试剂盒，代谢测定试剂盒，抗体和抗体/蛋白质微阵列的先驱。
品牌分类
\Elisa试剂盒\
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