Immunoway/AChRα3 Polyclonal Antibody/50ug 100ug/YT0082
市场价：
¥3200.00
美元价：
1600.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
AChRα3 Polyclonal Antibody
- Catalog No.：YT0082
- Applications：WB,ELISA
- Reactivity：Human,Mouse,Rat
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name：
- CHRNA3
- Protein Name：
- Neuronal acetylcholine receptor subunit alpha-3
- Human Gene Id：
- 1136
- Human Swiss Prot No：
- P32297
- Mouse Gene Id：
- 110834
- Mouse Swiss Prot No：
- Q8R4G9
- Rat Swiss Prot No：
- P04757
- Immunogen：
- The antiserum was produced against synthesized peptide derived from human AChRalpha3. AA range:90-139
- Specificity：
- AChRα3 Polyclonal Antibody detects endogenous levels of AChRα3 protein.
- Formulation：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source：
- Rabbit
- Dilution：
- Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
- Purification：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration：
- 1 mg/ml
- Storage Stability：
- -20°C/1 year
- Other Name：
- CHRNA3; NACHRA3; Neuronal acetylcholine receptor subunit alpha-3
- MolecularWeight(Da)：
- 57310
- Observed Band(KD)：
- 57
- Background：
- cholinergic receptor nicotinic alpha 3 subunit(CHRNA3)Homo sapiensThis locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009],
- Function：
- disease:Genetic variations in CHRNA3 may be associated with susceptibility to lung cancer type 2 (LNCR2) [MIM:612052].,disease:Genetic variations in CHRNA3 may be associated with susceptibility to peripheral arterial occlusive disease type 2 (PAOD2) [MIM:612052]. PAOD results from atherosclerosis of large and medium peripheral arteries, as well as the aorta. Many risk factors contribute to PAOD, including smoking, diabetes, hypertension, and hyperlipidemia. PAOD often coexists with coronary artery disease and cerebrovascular disease.,function:After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.,similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family.,subunit:Neuronal AChR is composed of two different types of subunits: alpha and beta. Alp
- Subcellular Location：
- plasma membrane,acetylcholine-gated channel complex,postsynaptic density,integral component of membrane,cell junction,dendrite,neuronal cell body,postsynaptic membrane,
- Expression：
- Brain,Keratinocyte,Lung,Thymus,
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- September 08-2020
- FLOW-CYTOMEYRT-PROTOCOL
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
- July 13-2018
- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using AChRα3 Polyclonal Antibody
- Western blot analysis of lysate from HeLa cells, using AChRα3 antibody.
品牌介绍
ImmunowayImmunoWay Biotechnology，我们的使命是帮助世界各地的生命科学研究人员通过更好的产品和服务简化和加速他们的研究。我们专注于开发用于免疫学和细胞学检测的创新和可靠的产品。我们一直是开发高质量ELISA试剂盒，代谢检测试剂盒，抗体和抗体/蛋白质微阵列的先驱，参与癌症，细胞凋亡，细胞生长和信号转导。ImmunoWay Biotechnology，我们的使命是通过更好的产品和服务帮助世界各地的生命科学研究者简化和加速他们的研究。我们专注于开发创新和可靠的产品，用于免疫学和细胞学检测。我们一直是开发涉及癌症，细胞凋亡，细胞生长和信号转导的高质量ELISA试剂盒，代谢测定试剂盒，抗体和抗体/蛋白质微阵列的先驱。
品牌分类
\Elisa试剂盒\
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