免疫法/盐酸阿霉素/50mg 100mg/MC0051
市场价：
¥0.00
美元价：
0.00
产品分类：
定量试剂盒
公司分类：
Quantitation_Kits
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Doxorubicin hydrochloride
- Catalog No.：MC0051
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- CasNo：
- 25316-40-9
- MolecularFormula：
- C27H29NO11.HCl
- Purity：
- 99%
- Target：
- Topoisomerase
- IC50：
- No data
- In Vitro：
- Combination of Doxorubicin and Simvastatin in the highest tested concentrations (2 μM and 10 μM, respectively) kills 97% of the Hela cells[2].
- In Vivo：
- Mice bearing PC3 xenografts are injected with 2, 4 or 8 mg/kg Doxorubicin and tumor volume is measured over time. A dose of 2 mg/kg does not affect tumor growth while higher dosages delay tumor growth initially (p<0.05 at="" days="" 18="" and="" 22),="" 4="" mg/kg="" or="" 8="" mg/kg="" doxorubicin="" significantly="" reduces="" levels="" of="" c-flip="" in="" pc3="" xenografts[3].="" a="" single="" intraperitoneal="" injection="" 10="" mg/kg="" (doxorubicin="" 1)="" is="" administered="" in="" rats,="" 10="" daily="" intraperitoneal="" injections="" of="" 1="" mg/kg="" (doxorubicin="" 2),="" or="" in="" 5="" weekly="" intraperitoneal="" injections="" of="" 2="" mg/kg="" (doxorubicin="" 3).="" an="" 80%="" mortality="" rate="" is="" observed="" at="" day="" 28="" in="" doxorubicin="" 1,="" whereas="" doxorubicin="" 2="" and="" doxorubicin="" 3="" reached="" 80%="" mortality="" at="" days="" 107="" and="" 98,="" respectively.="" fractional="" shortening="" decreased="" by="" 30%="" at="" week="" 2="" in="" doxorubicin="" dox1,="" 55%="" at="" week="" 13="" in="" doxorubicin="" 2,="" and="" 42%="" at="" week="" 13="" in="" doxorubicin="">
- Fields：
- Doxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
- Specificity：
- Target:Topoisomerase. Fields: Doxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
- Source：
- Rabbit
- Dilution：
- WB 1:500-2000
- Concentration：
- 99%
- Storage Stability：
- 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
- MolecularWeight(Da)：
- 579.98
- References：
- [1]. Nitiss JL, et al. Targeting DNA topoisomerase II in cancer chemotherapy.Nat Rev Cancer. 2009 May;9(5):338-50.[2]. Sadeghi-Aliabadi H, et al. Cytotoxic evaluation of doxorubicin in combination wi
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品牌介绍
ImmunowayImmunoWay Biotechnology，我们的使命是帮助世界各地的生命科学研究人员通过更好的产品和服务简化和加速他们的研究。我们专注于开发用于免疫学和细胞学检测的创新和可靠的产品。我们一直是开发高质量ELISA试剂盒，代谢检测试剂盒，抗体和抗体/蛋白质微阵列的先驱，参与癌症，细胞凋亡，细胞生长和信号转导。ImmunoWay Biotechnology，我们的使命是通过更好的产品和服务帮助世界各地的生命科学研究者简化和加速他们的研究。我们专注于开发创新和可靠的产品，用于免疫学和细胞学检测。我们一直是开发涉及癌症，细胞凋亡，细胞生长和信号转导的高质量ELISA试剂盒，代谢测定试剂盒，抗体和抗体/蛋白质微阵列的先驱。
品牌分类
\Elisa试剂盒\
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