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商品详细免疫法/TORC1/CRTC1(磷酸化Ser151)兔pAb/20ug 50ug 100ug/YP1534
免疫法/TORC1/CRTC1(磷酸化Ser151)兔pAb/20ug 50ug 100ug/YP1534
免疫法/TORC1/CRTC1(磷酸化Ser151)兔pAb/20ug 50ug 100ug/YP1534
商品编号: YP1534
品牌: Immunoway
市场价: ¥1700.00
美元价: 850.00
产地: 美国(厂家直采)
公司:
产品分类: RIA放免试剂盒
公司分类: RIA
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

TORC1/CRTC1 (phospho-Ser151) rabbit pAb

  • Catalog No.:YP1534
  • Applications:WB
  • Reactivity:Human
  • Data Sheet
  • MSDS
  • Support
  • Description
  • References ( 0 )
  • Protocol
    • Gene Name:
    • CRTC1 KIAA0616 MECT1 TORC1 WAMTP1
    • Protein Name:
    • TORC1/CRTC1 (Ser151)
    • Human Gene Id:
    • 23373
    • Human Swiss Prot No:
    • Q6UUV9
    • Mouse Gene Id:
    • 382056
    • Mouse Swiss Prot No:
    • Q68ED7
    • Rat Gene Id:
    • 684527
    • Rat Swiss Prot No:
    • Q157S1
    • Immunogen:
    • Synthesized phosho peptide around human TORC1 and CRTC1 (Ser151)
    • Specificity:
    • This antibody detects endogenous levels ofHuman TORC1 or CRTC1 (phospho-Ser151)
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • WB 1:1000-2000
    • Purification:
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Other Name:
    • CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1)
    • Observed Band(KD):
    • 70
    • Function:
    • disease:A chromosomal aberration involving CRTC1 is found in mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas. Translocation t(11;19)(q21;p13) with MAML2. The fusion protein consists of the N-terminus of CRTC1 joined to the C-terminus of MAML2. The reciprocal fusion protein consisting of the N-terminus of MAML2 joined to the C-terminus of CRTC1 has been detected in a small number of mucoepidermoid carcinomas.,function:Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 "Ser-133" phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator
    • Subcellular Location:
    • nucleus,nucleoplasm,cytoplasm,plasma membrane,dendrite,neuronal cell body,synapse,
    • Expression:
    • Brain,Carcinoma,Colon,Embryo,Eye,
    • June 19-2018
    • WESTERN IMMUNOBLOTTING PROTOCOL
    • June 19-2018
    • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
    • June 19-2018
    • IMMUNOFLUORESCENCE PROTOCOL
    • June 19-2018
    • FLOW CYTOMEYRT PROTOCOL
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
    • July 13-2018
    • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
    • July 13-2018
    • Antibody-FAQs
    品牌介绍
    ImmunowayImmunoWay Biotechnology,我们的使命是帮助世界各地的生命科学研究人员通过更好的产品和服务简化和加速他们的研究。我们专注于开发用于免疫学和细胞学检测的创新和可靠的产品。我们一直是开发高质量ELISA试剂盒,代谢检测试剂盒,抗体和抗体/蛋白质微阵列的先驱,参与癌症,细胞凋亡,细胞生长和信号转导。ImmunoWay Biotechnology,我们的使命是通过更好的产品和服务帮助世界各地的生命科学研究者简化和加速他们的研究。我们专注于开发创新和可靠的产品,用于免疫学和细胞学检测。我们一直是开发涉及癌症,细胞凋亡,细胞生长和信号转导的高质量ELISA试剂盒,代谢测定试剂盒,抗体和抗体/蛋白质微阵列的先驱。