免疫法/TAB2（磷酸化Ser372）兔pAb/20ug 50ug 100ug/YP1520
市场价：
¥1700.00
美元价：
850.00
产品分类：
DNA提取纯化试剂
公司分类：
DNA_extraction
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
TAB2 (phospho-Ser372)rabbit pAb
- Catalog No.：YP1520
- Applications：WB
- Reactivity：Human,Mouse,Rat
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name：
- TAB2 KIAA0733 MAP3K7IP2
- Protein Name：
- TAB2 (Ser372)
- Human Gene Id：
- 23118
- Human Swiss Prot No：
- Q9NYJ8
- Mouse Gene Id：
- 68652
- Mouse Swiss Prot No：
- Q99K90
- Rat Gene Id：
- 308267
- Rat Swiss Prot No：
- Q5U303
- Immunogen：
- Synthesized phosho peptide around human TAB2 (Ser372)
- Specificity：
- This antibody detects endogenous levels ofHuman Mouse Rat TAB2 (phospho-Ser372)
- Formulation：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source：
- Rabbit
- Dilution：
- WB 1:1000-2000
- Purification：
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration：
- 1 mg/ml
- Storage Stability：
- -20°C/1 year
- Other Name：
- TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
- Observed Band(KD)：
- 77
- Background：
- TGF-beta activated kinase 1/MAP3K7 binding protein 2(TAB2)Homo sapiensThe protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects, multiple types, 2 (CHTD2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],
- Function：
- function:Adapter linking MAP3K7/TAK1 and TRAF6 and mediator of MAP3K7 activation in the IL1 signaling pathway.,PTM:Phosphorylated.,PTM:Ubiquitinated; following IL1 stimulation or TRAF6 overexpression.,similarity:Contains 1 CUE domain.,similarity:Contains 1 RanBP2-type zinc finger.,subcellular location:Following IL1 stimulation, translocation occurs from the membrane to cytosol.,subunit:Interacts with MAP3K7 and TRAF6. Interacts with NCOR1 and HDAC3 to form a ternary complex.,tissue specificity:Widely expressed.,
- Subcellular Location：
- cytosol,plasma membrane,endosome membrane,
- Expression：
- Brain,Eye,Kidney,Testis,
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- June 19-2018
- FLOW CYTOMEYRT PROTOCOL
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
- July 13-2018
- Antibody-FAQs
品牌介绍
ImmunowayImmunoWay Biotechnology，我们的使命是帮助世界各地的生命科学研究人员通过更好的产品和服务简化和加速他们的研究。我们专注于开发用于免疫学和细胞学检测的创新和可靠的产品。我们一直是开发高质量ELISA试剂盒，代谢检测试剂盒，抗体和抗体/蛋白质微阵列的先驱，参与癌症，细胞凋亡，细胞生长和信号转导。ImmunoWay Biotechnology，我们的使命是通过更好的产品和服务帮助世界各地的生命科学研究者简化和加速他们的研究。我们专注于开发创新和可靠的产品，用于免疫学和细胞学检测。我们一直是开发涉及癌症，细胞凋亡，细胞生长和信号转导的高质量ELISA试剂盒，代谢测定试剂盒，抗体和抗体/蛋白质微阵列的先驱。
品牌分类
\Elisa试剂盒\
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