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Immunoway/Dab1 (phospho-Tyr220) rabbit pAb/20ug 50ug 100ug/YP1309
Immunoway/Dab1 (phospho-Tyr220) rabbit pAb/20ug 50ug 100ug/YP1309
市场价：
¥1700.00
美元价：
850.00
产品分类：
蛋白纯化试剂盒
公司分类：
Protein_purification_kit
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Dab1 (phospho-Tyr220) rabbit pAb
- Catalog No.：YP1309
- Applications：WB
- Reactivity：Human
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name：
- DAB1
- Protein Name：
- Dab1 (Tyr220)
- Human Gene Id：
- 1600
- Human Swiss Prot No：
- O75553
- Mouse Gene Id：
- 13131
- Mouse Swiss Prot No：
- P97318
- Rat Gene Id：
- 266729
- Rat Swiss Prot No：
- Q8CJH2
- Immunogen：
- Synthesized phosho peptide around human Dab1 (Tyr220)
- Specificity：
- This antibody detects endogenous levels ofHuman Dab1 (phospho-Tyr220)
- Formulation：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source：
- Rabbit
- Dilution：
- WB 1:1000-2000
- Purification：
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration：
- 1 mg/ml
- Storage Stability：
- -20°C/1 year
- Other Name：
- Disabled homolog 1
- Observed Band(KD)：
- 60
- Background：
- DAB1, reelin adaptor protein(DAB1)Homo sapiensThe laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008],
- Function：
- domain:The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.,function:Adapter molecule functioning in neural development. May regulate SIAH1 activity.,PTM:Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.,similarity:Contains 1 PID domain.,subunit:Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1.,
- Subcellular Location：
- nucleolus,microtubule organizing center,cytosol,brush border,postsynaptic density,membrane,neuron projection,neuronal cell body,intracellular membrane-bounded organelle,apical part of cell,perinuclear region of cytoplasm,
- Expression：
- Brain,
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- June 19-2018
- FLOW CYTOMEYRT PROTOCOL
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
- July 13-2018
- Antibody-FAQs
品牌介绍
ImmunowayImmunoWay Biotechnology，我们的使命是帮助世界各地的生命科学研究人员通过更好的产品和服务简化和加速他们的研究。我们专注于开发用于免疫学和细胞学检测的创新和可靠的产品。我们一直是开发高质量ELISA试剂盒，代谢检测试剂盒，抗体和抗体/蛋白质微阵列的先驱，参与癌症，细胞凋亡，细胞生长和信号转导。ImmunoWay Biotechnology，我们的使命是通过更好的产品和服务帮助世界各地的生命科学研究者简化和加速他们的研究。我们专注于开发创新和可靠的产品，用于免疫学和细胞学检测。我们一直是开发涉及癌症，细胞凋亡，细胞生长和信号转导的高质量ELISA试剂盒，代谢测定试剂盒，抗体和抗体/蛋白质微阵列的先驱。
品牌分类
\Elisa试剂盒\
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