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当前位置: 首页 > 产品中心 > Targeted_sequencing_kit > Immunoway/Numb (phospho-Ser276) rabbit pAb/20ug 50ug 100ug/YP1424
商品详细Immunoway/Numb (phospho-Ser276) rabbit pAb/20ug 50ug 100ug/YP1424
Immunoway/Numb (phospho-Ser276)  rabbit pAb/20ug 50ug 100ug/YP1424
Immunoway/Numb (phospho-Ser276) rabbit pAb/20ug 50ug 100ug/YP1424
商品编号: YP1424
品牌: Immunoway
市场价: ¥1700.00
美元价: 850.00
产地: 美国(厂家直采)
公司:
产品分类: 靶向测序试剂盒
公司分类: Targeted_sequencing_kit
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Numb (phospho-Ser276)rabbit pAb

  • Catalog No.:YP1424
  • Applications:WB
  • Reactivity:Human
  • Data Sheet
  • MSDS
  • Support
  • Description
  • References ( 0 )
  • Protocol
    • Gene Name:
    • NUMB
    • Protein Name:
    • Numb (Ser276)
    • Human Gene Id:
    • 8650
    • Human Swiss Prot No:
    • P49757
    • Mouse Gene Id:
    • 18222
    • Mouse Swiss Prot No:
    • Q9QZS3
    • Rat Swiss Prot No:
    • Q2LC84
    • Immunogen:
    • Synthesized phosho peptide around human Numb (Ser276)
    • Specificity:
    • This antibody detects endogenous levels ofHuman Numb (phospho-Ser276)
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • WB 1:1000-2000
    • Purification:
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Other Name:
    • Protein numb homolog (h-Numb) (Protein S171)
    • Observed Band(KD):
    • 70
    • Background:
    • NUMB, endocytic adaptor protein(NUMB) Homo sapiensThe protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
    • Function:
    • function:Implicated in the control of cell fate decisions during development.,PTM:Isoform 1 and isoform 2 are ubiquitinated by LNX leading to their subsequent proteasomal degradation (By similarity). Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,sequence caution:Intron retention.,similarity:Contains 1 PID domain.,subunit:Interacts with EPS15, LNX and NOTCH1. May interact with DUOXA1. Interacts with RALBP1 in a complex also containing EPN1 and TFAP2A during interphase and mitosis.,
    • Subcellular Location:
    • nucleus,early endosome,plasma membrane,cell-cell adherens junction,focal adhesion,cytoplasmic, membrane-bounded vesicle,basolateral plasma membrane,extrinsic component of plasma membrane,clathrin-coated vesicle,apical part of cell,
    • Expression:
    • B cells,Blood,Brain,Cervix carcinoma,Epithelium,Fetal brain,HeLa cells,Live
    • June 19-2018
    • WESTERN IMMUNOBLOTTING PROTOCOL
    • June 19-2018
    • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
    • June 19-2018
    • IMMUNOFLUORESCENCE PROTOCOL
    • June 19-2018
    • FLOW CYTOMEYRT PROTOCOL
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
    • July 13-2018
    • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
    • July 13-2018
    • Antibody-FAQs
    品牌介绍
    ImmunowayImmunoWay Biotechnology,我们的使命是帮助世界各地的生命科学研究人员通过更好的产品和服务简化和加速他们的研究。我们专注于开发用于免疫学和细胞学检测的创新和可靠的产品。我们一直是开发高质量ELISA试剂盒,代谢检测试剂盒,抗体和抗体/蛋白质微阵列的先驱,参与癌症,细胞凋亡,细胞生长和信号转导。ImmunoWay Biotechnology,我们的使命是通过更好的产品和服务帮助世界各地的生命科学研究者简化和加速他们的研究。我们专注于开发创新和可靠的产品,用于免疫学和细胞学检测。我们一直是开发涉及癌症,细胞凋亡,细胞生长和信号转导的高质量ELISA试剂盒,代谢测定试剂盒,抗体和抗体/蛋白质微阵列的先驱。