Immunoway/ACTA2 Monoclonal Antibody/50ug 100ug/YM0011
市场价：
¥4200.00
美元价：
2100.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
ACTA2 Monoclonal Antibody
- Catalog No.：YM0011
- Applications：WB,IHC-p,IF/ICC,FCM,ELISA
- Reactivity：Human,Mouse,Rat,Monkey
- Data Sheet
- MSDS
- Support
- Description
- References ( 0 )
- Protocol
- Gene Name：
- ACTA2
- Protein Name：
- Actin, aortic smooth muscle
- Human Gene Id：
- 59
- Human Swiss Prot No：
- P62736
- Mouse Gene Id：
- 11475
- Mouse Swiss Prot No：
- P62737
- Rat Gene Id：
- 81633
- Rat Swiss Prot No：
- P62738
- Immunogen：
- Synthesized peptide of human ACTA2.
- Specificity：
- ACTA2 Monoclonal Antibody detects endogenous levels of ACTA2 protein.
- Formulation：
- Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
- Source：
- Mouse
- Dilution：
- Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.
- Purification：
- Affinity purification
- Storage Stability：
- -20°C/1 year
- Other Name：
- ACTA2; ACTSA; ACTVS; GIG46; Actin;aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein
- References：
- 1. J Hum Genet. 2009 Nov;54(11):687-8. 2. Hum Mutat. 2009 Oct;30(10):1406-11.
- Background：
- actin, alpha 2, smooth muscle, aorta(ACTA2) Homo sapiensThe protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008],
- Function：
- disease:Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as "medial necrosis" or "Erdheim cystic medial necrosis" in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.,function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.,miscellaneous:In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actin
- Subcellular Location：
- extracellular space,cytoplasm,cytosol,actin cytoskeleton,lamellipodium,filopodium,smooth muscle contractile fiber,protein complex,cell body,extracellular exosome,
- Expression：
- Pituitary,Uterus,
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- September 08-2020
- FLOW-CYTOMEYRT-PROTOCOL
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
- July 13-2018
- Antibody-FAQs
- Products Images
- Western Blot analysis using ACTA2 Monoclonal Antibody against HeLa (1), A431 (2), Jurkat (3), K562 (4), HEK293 (5), HepG2 (6), NIH/3T3 (7), PC-12 (8) and Cos7 (9) cell lysate.
- Immunohistochemistry analysis of paraffin-embedded human duodenum tissues (left) and human esophagus tissues (right) with DAB staining using ACTA2 Monoclonal Antibody.
- Immunofluorescence analysis of HepG2 cells using ACTA2 Monoclonal Antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
- Flow cytometric analysis of Hela cells using ACTA2 Monoclonal Antibody (green) and negative control (purple).
品牌介绍
ImmunowayImmunoWay Biotechnology，我们的使命是帮助世界各地的生命科学研究人员通过更好的产品和服务简化和加速他们的研究。我们专注于开发用于免疫学和细胞学检测的创新和可靠的产品。我们一直是开发高质量ELISA试剂盒，代谢检测试剂盒，抗体和抗体/蛋白质微阵列的先驱，参与癌症，细胞凋亡，细胞生长和信号转导。ImmunoWay Biotechnology，我们的使命是通过更好的产品和服务帮助世界各地的生命科学研究者简化和加速他们的研究。我们专注于开发创新和可靠的产品，用于免疫学和细胞学检测。我们一直是开发涉及癌症，细胞凋亡，细胞生长和信号转导的高质量ELISA试剂盒，代谢测定试剂盒，抗体和抗体/蛋白质微阵列的先驱。
品牌分类
\Elisa试剂盒\
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